Endocrine Abstracts

The present study aimed to explore the relationship of sarcopenia, with or without the presence of obesity, with the risk of developing type 2 diabetes. We conducted a cross-sectional analysis of 2981 subjects in the Korean Genome and Epidemiology Study. The diabetes status of each subject was determined by using a 75 g oral glucose tolerance test, and body composition was estimated via dual-energy X-ray absorptiometry. The skeletal muscle mass index (SMI, %) was obtained by c...

Current guidelines on cardiovascular (CV) disease prevention recommend targeted management after assessment of CV risks using many of available method even if the patient is asymptomatic. This study was performed to explore how CV high-risk is differently detected between two distinct methods: non-invasive test (NIT) and risk calculation and how the awareness of CV high-risk impacts physician and patient behavior for risk management in diabetes patient.A...

Background and aims: The efficacy and safety of dapagliflozin as add-on therapy in patients with type 2 diabetes mellitus (T2DM) and inadequate glycemic control with evogliptin and metformin combinations was investigated.Materials and methods: Patients with HbA1c of 7.0% to 10.5% receiving evogliptin 5mg and metformin ≥1000 mg were randomized to receive dapagliflozin 10 mg/day (n=99) or placebo (n=99) for 24 weeks. The primary end...

Introduction: This study aimed to examine whether altered Heart Rate Variability (HRV) could predict the risk of development of metabolic syndrome (MetSD) in Asians.Methods: We investigated health checkup records of 33 752 adults aged 20–65 years old who did health checkups and HRV measurement between April 2011 and June 2014 at Kangbuk Samsung Hospital, without MetSD, anemia, thyroid disease, malignancy, and heart disease. A 3-minute HRV recording ...